Encephalopathy with pathological climax — myth or reality

Abstract

The article presents the results of a clinical and paraclinical examination of women with climacteric encephalopathy with the aim of investigating possible pathogenetic mechanisms of its development and verifying the diagnosis. Complaints, neurological status, psychoemotional state of women were analyzed, microcirculatory channel, blood flow through the main arteries of the brain, electroencephalography data, as well as the processes of lipid peroxidation, endogenous intoxication, nucleic exchange and nitric oxide exchange in the specified category of patients were analyzed. In view of the results of the study, a conclusion was made about the validity of the existence and diagnosis of climacteric encephalopathy in women, however, the diagnosis, taking into account the non-specificity of the results of diagnostic tests, requires the clinician to have an understanding of the probable pathogenetic mechanisms of its development and skills in conducting additional instrumental examinations, which can testify to partially reversed functional changes in the brain. Only the combination of extensive clinical experience with the specified knowledge can help in differential diagnosis and final diagnosis of climact eric encephalopathy.