STATE OF THYROID AND ADRENOCORTICOID FUNCTIONS IN CHILDREN WITH SYNDROME OF BIOLOGICALLY INACTIVE GROWTH HORMON
No. 3 (2018), ENDOCRINE SYSTEM COMORBIDITY STATES
No. 3 (2018)

STATE OF THYROID AND ADRENOCORTICOID FUNCTIONS IN CHILDREN WITH SYNDROME OF BIOLOGICALLY INACTIVE GROWTH HORMON

ENDOCRINE SYSTEM COMORBIDITY STATES
Published September 20, 2018
N.A. Sprynchuk
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Keywords

syndrome of biologically inactive growth hormone, thyrotropic function, adrenocorticotropic function, children, recombinant growth hormone

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Sprynchuk, N. (2018). STATE OF THYROID AND ADRENOCORTICOID FUNCTIONS IN CHILDREN WITH SYNDROME OF BIOLOGICALLY INACTIVE GROWTH HORMON. The Practitioner, (3), 9-12. Retrieved from https://plr.com.ua/index.php/journal/article/view/26
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Abstract

The aim of this work was to study the features of thyrotropic and adrenocorticotropic functions in patients with syndrome of biologically inactive growth hormone. There were examined 158 children with this syndrome, among them 49 girls and 109 boys, whose average age was 8.3±0.24 years, 128 children had prepubertal, 30 children — pubertal age. TSH, fT4, ACTH, and cortisol were studied before and during 6 months of treatment with a recombinant growth hormone. Analyzing the results of the study, no the disturbances in thyrotropic and adenocorticotropic functions of the body in patients with syndrome of biologically inactive growth hormone were revealed. Reserve adaptive mechanisms of the hypothalamic-pituitary-thyroid and the hypothalamus-pituitary-adrenal systems have an adequate responses to long-term treatment with recombinant growth hormone preparations.

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