Sedafiton Forte in the treatment of disorders of circadian rhythms
pdf (Українська)

Keywords

circadian rhythm, insomnia, sleep disorders, melatonin, Sedafiton Forte.

How to Cite

Voloshyna, N., Vasylovskyy, V., Chernenko, M., & Vovk, V. (2016). Sedafiton Forte in the treatment of disorders of circadian rhythms. The Practitioner, (3), 45-48. Retrieved from https://plr.com.ua/index.php/journal/article/view/156

Abstract

In the article was considered the problem of insomnia, circadian rhythm sleep-wake, as well as ways of treating of sleep disorders. A correction of insomnia with Sedafiton Forte was proposed. In the studied group of patients with disorders of the circadian rhythm of sleep-wake high efficacy and good tolerabilityof Sedafiton Forte were determined in all patients. Reduction of clinical manifestations correlated with improvements of laboratory parameters, of expression day and night melatonin and cortisol expression. Persistent clinical remission was achieved in 83.3% of cases. Results of the study allow to recommend Sedafiton Forte as medication for treating of circadian rhythm sleep-wake due to the fact that the drug was well tolerated and has no allergic activity, easy to use.

pdf (Українська)

References

1. Анисимов С.В., Хавинсон В.Х., Анисимов В.Н. Влияние мелатонина и тетрапептида на экспрессию генов в головном мозге мышей // Бюл. экспер.
биол. мед. — 2004. — № 138. — С. 570-576.
2. Виноградова И.А., Шевченко А.И. Влияние светового режима на показатели биологического возраста и возрастную патологию // Мед. акад. ж. —
2005. — № 5 (приложение 7). — С. 18-20.
3. Комаров Ф.И., Рапопорт С.И., Малиновская Н.К., Анисимов В.Н. Мелатонин в норме и патологии. — М.: ИД «Медпрактика», 2004. — 308 с.
4. Левин Я.И. Инсомния: современные диагностические и лечебные подходы. — М.: Медпрактика, 2005. — 116 с.
5. Ром-Бугославская Е.С., Бондаренко Л.А., Сомова Е.В., Комарова И.В. Роль пинеальной железы в развитии атеросклероза. Влияние круглосуточного освещения на некоторые стороны патогенеза атеросклероза // Пробл. cтарения и долголетия. — 1993. — № 2. — С. 91-97.
6. Abarran M.T., Lopez-Burillo S., Pablos M.I. et al. Endogenous rhythms of melatonin, total antioxidant status and superoxide dismutase activity in several tissues
of chick and their inhibition by light // J. Pineal Res. — 2001. — Vol. 30. — Р. 227-233.
7. Anisimov S.V., Popovic N. Genetic aspects of melatonin biology // Rev. Neurosci. — 2004. — Vol. 15. — Р. 209-230.
8. Anisimov V.N. Effect of melatonin on life span and longevity. In: Melatonin: Biological Basis of Its Function in Health and Disease / S.R. Pandi-Perumal, D.P. Cardinali, eds. — Georgetown, TX: Landes Bioscience, 2006. — Р. 45-59.
9. Arendt J. Melatonin: characteristics, concerns, and prospects // J. Biol. Rhythms. — 2005. — Vol. 20. — Р. 291-303.
10. Donath F., Quispe S., Diefenbach K., Maurer A., Fietze I., Roots I. Critical evaluation of the effect of valerian extract on sleep structure and sleep quality //
Pharmacopsychiatry. — 2000. — Vol. 33. — Р. 47-53.
11. Dundar Y., Boland A., Strobl J. et al. Newer hypnotic drugs for the short-term management of insomnia: a systematic review and economic evaluation // Health
Technol. Assess. — 2004. — Vol. 8. — Р. 1-125.
12. Hofman M.A., Swaab D.F. Living by the clock: The circadian pacemaker in older people // Ageing Res. Rev. — 2006. — Vol. 5. — Р. 33-51.
13. Hurd M.W., Ralph M.R. The significance of circadian organization for longevity in the golden hamster // J. Biol. Rhythms. — 1998. — Vol. 13. — Р. 430-436.
14. Lie J.D., Tu K.N., Shen D.D. and Wong B.M. Pharmacological Treatment of Insomnia // Pharmacy and Therapeutics. — 2015 Nov. — Vol. 40 (11). — Р. 759-768, 771.
15. Knutsson A. Health disorders of shift workers // Occup. Med. — 2003. — Vol. 53. — Р. 103-108.

Downloads

Download data is not yet available.