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Abstract
The work is devoted to studing the influence of uric acid on the course of arterial hypertension. Purpose. To study the gender and sex characteristics of the state of lipid, carbohydrate, fat metabolism in patients with arterial hypertension depending on the level of uric acid. Materials and methods. 98 patients (42 men and 54 women) with stage II hypertension of 1-3 degrees were examined, the average age of which was 54.6±8.1 years. Patients were divided into 2 groups. Group I (n=59) — patients with hypertension and hyperuricemia, Group II (n=39) — patients with hypertension without hyperuricemia. The control group consisted of 20 practically healthy persons without signs of hypertension, representative in terms of age and sex. The results. It has been found that the level of uric acid in the examined patients exceeded the indicators of practically healthy persons in
women by 49.1% (р˂0.01), and in men by 20.8%. The highest level of uric acid was observed at the age under 60 years (р˂0.05). An increase in uric acid concentration in patients with hypertension is associated with an increase in TG, glycated hemoglobin and a decrease in HDL. Conclusions. In patients with hypertension, hyperuricemia is significantly more common in women than in men and at the age under 60 years. In the case of a combination of hypertension with hyperuricemia, more pronounced disorders of lipid, fat, and carbohydrate metabolism have been established.
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