Keywords
Infectious mononucleosis, Epstein-Barr virus, children, treatment, interferon, acyclic nucleoside analog, immunogenesis, immune dysfunction, immune deficiency, probiotics.
How to Cite
VygovskаyaО., Kramarev, S., Doroshenko, V., & Shpak, I. (2012). EBV Infectious mononucleosis in children: etiology, pathogenesis, immunogenesis, treatment. The Practitioner, (4), 29-34. Retrieved from https://plr.com.ua/index.php/journal/article/view/545
Abstract
The article deals with the etiology, pathogenesis, immunogenesis of infectious mononucleosis in children, analyzes the literature on the treatment of infectious mononucleosis in children, presents the results of authors research on the state of immunity EBV infectious mononucleosis in children, the results the treatment of infectious mononucleosis with the inclusion of probiotics.
References
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3. Erickson KH, Hubbard NE. Probiotic immunomodulation in health and disease. J Nutr. 2000; 130: 403S–409S
4. Foerster J. Infectious mononucleosis. In: Lee. Wintrobe’s Clinical Hematology. 10 th ed. 1999: 1926–1955.
5. Fota-Markowcka H. et al. Profile of microorganisms isolated in nasopharyngeal swabs from the patients with acute infectious mononucleosis // Wiad. Lek. 2002; 55; 3–4: 150–157.
6. Furman P. A., de Miranda P., St. Clair M. H. et al. Metabolism of acyclovir in virus-infected and uninfected cells. Antimicrob // Agents Chemother. 1981; 20: 518–524.
7. Gershburg E., Pagano J. S. Epstein-Barr infections: prospects for treatment // Journal of Antimicrobial Chemotherapy. 2005; 56; 2: 277–281.
8. Glenda C. Faulkner, Andrew S. Krajewski and Dorothy H. CrawfordA The infectious mononucleosis and outs of EBV infеction // Trends in Microbiology. 2000; 8: 185–189.
9. Kawa K. Epstein-Barr virus-associated diseases in humans // Inf. J. Hematol.; 2000; 71: 108-117.
10. Meerbach A. et al. Inhibitory effects of novel nucleoside and nucleotide analogues on Epstein-Barr virus replication // Antivir. Chem. Chemother. 1998; 9; 3: 275–282.
11. Roy M., Bailey B., Amre D. K. et al. Dexamethasone for the treatment of sore throat in children with suspected infectious mononucleosis: a randomized, double-blind, placebo-controlled, clinical trial // Archiv Pediatric Adolescent Med. 2004; 158: 250–254.
12. Thracker E. L., Mirzaei F., Ascherio A. Infectious mononucleosis and risk for multiple sclerosis: a metaanalysis // Ann. Neurol. 2006; 59; 3: 499–503.
13. Van der Horst C., Joncas J., Ahronheim G. et al. Lack of effect of peroral acyclovir for the treatment of acute infectious mononucleosis // J Infect Dis. 1991; 164: 788–792.
14. Блохина Е.Б. Роль латентной инфекции, вызванной вирусом Эпштейна-Барр, в развитии лимфопролиферативных заболеваний // Вопросы гематологии/онкологии и иммунопатологии в педиатрии. - 2003. - Т.2. - № 3. - С. 65-70.
15. Глей А.І. Хронічні форми Епштейн-Барр вірусної інфекції //Клінічна імунологія. Алергологія. Інфектологія. – 2009. – № 2. – С. 69-71.
2. Craig M.V.,Clare N., Skar J.L., Banks P.M. T-cell lymphoma and virus-associated hemophagocytic syndrome // Am.J.Clin.Pathol.; 1992; 97: 189-94.
3. Erickson KH, Hubbard NE. Probiotic immunomodulation in health and disease. J Nutr. 2000; 130: 403S–409S
4. Foerster J. Infectious mononucleosis. In: Lee. Wintrobe’s Clinical Hematology. 10 th ed. 1999: 1926–1955.
5. Fota-Markowcka H. et al. Profile of microorganisms isolated in nasopharyngeal swabs from the patients with acute infectious mononucleosis // Wiad. Lek. 2002; 55; 3–4: 150–157.
6. Furman P. A., de Miranda P., St. Clair M. H. et al. Metabolism of acyclovir in virus-infected and uninfected cells. Antimicrob // Agents Chemother. 1981; 20: 518–524.
7. Gershburg E., Pagano J. S. Epstein-Barr infections: prospects for treatment // Journal of Antimicrobial Chemotherapy. 2005; 56; 2: 277–281.
8. Glenda C. Faulkner, Andrew S. Krajewski and Dorothy H. CrawfordA The infectious mononucleosis and outs of EBV infеction // Trends in Microbiology. 2000; 8: 185–189.
9. Kawa K. Epstein-Barr virus-associated diseases in humans // Inf. J. Hematol.; 2000; 71: 108-117.
10. Meerbach A. et al. Inhibitory effects of novel nucleoside and nucleotide analogues on Epstein-Barr virus replication // Antivir. Chem. Chemother. 1998; 9; 3: 275–282.
11. Roy M., Bailey B., Amre D. K. et al. Dexamethasone for the treatment of sore throat in children with suspected infectious mononucleosis: a randomized, double-blind, placebo-controlled, clinical trial // Archiv Pediatric Adolescent Med. 2004; 158: 250–254.
12. Thracker E. L., Mirzaei F., Ascherio A. Infectious mononucleosis and risk for multiple sclerosis: a metaanalysis // Ann. Neurol. 2006; 59; 3: 499–503.
13. Van der Horst C., Joncas J., Ahronheim G. et al. Lack of effect of peroral acyclovir for the treatment of acute infectious mononucleosis // J Infect Dis. 1991; 164: 788–792.
14. Блохина Е.Б. Роль латентной инфекции, вызванной вирусом Эпштейна-Барр, в развитии лимфопролиферативных заболеваний // Вопросы гематологии/онкологии и иммунопатологии в педиатрии. - 2003. - Т.2. - № 3. - С. 65-70.
15. Глей А.І. Хронічні форми Епштейн-Барр вірусної інфекції //Клінічна імунологія. Алергологія. Інфектологія. – 2009. – № 2. – С. 69-71.
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