Functional state of gallbladder in patients with metabolic syndrome according to diet

Abstract

The influence of diet on functional state of gallbladder (GB) in patients with metabolic syndrome (MS) was investigated using dynamic echocholecystogragraphy and multiple duodenal intubation. 72 outpatients of middle age with obesity I-II stage and with signs of MS but without diabetes mellitus were observed. Patients with MS have signs of hypotonic and hypokinetic dyskinesia of GB. Severity of dyskinesia depends on the diet of a
patient. It is determined that patients with MS with prevalence of carbohydrates in diet have significant decrease of contractile ability of GB than in patients with MS and balanced diet – the phenomenon of unresponsiveness of GB when there is no secretion of gallbladder bile after insertion of standard cholekinetics. Thereby the excess of carbohydrates in diet in patients with MS enhance disturbance of contractile ability of GB and may further progression of the disease.