Abstract
There are the difficulties in defining and classifying the new different clinical phenotypes of COPD such as overlapped asthmaCOPD; frequently exacerbated; emphysemic-hyperinflated, fasted FEV1 falling, deficient of α1-antytripsine, cachectic and eosinophilia in sputum. These phenotypes may help to interpersonal differentiation among COPD patients. Some of national guidelines propose a phenotype-guided therapy of COPD. Recognizing the different phenotypes within COPD is very important for better understanding the underlining disease processes as well as for the clinicians due to differing response to GOLD scheme of COPD therapy.
References
1. Standards for the diagnosis and care of patients with COPD. American Thoracic Society // Am. J. Respir. Crit. Care Med. — 1995. — Vol. 152. — P. S77-121.
2. Vestbo J., Hurd S.S., Augusti A.G. et al. Global strategy for the diagnosis, management and prevention of COPD — GOLD executive summary // Am. J. Respir. Crit. Care Med. — 2013. — Vol. 187. — P. 347-365.
3. Bednarek M., Sliwinsky P. Fenotypy przewlekłej obturacyjnej choroby płuc // Terapia. — 2015. — № 9. — S. 6-11.
4. Pierzchala W. Fenotyp POChP: różnice patogenetyczne i terapeutyczne // Terapia. — 2016. — № 3. — S. 32-35.
5. Miravitles M., Calle M., Soler-Cataluna J.J. Clinical phenotypes of COPD: identification, definition and implications for guidelines // Arch. Broncopneumol. — 2012. — Vol. 48. — P. 86-98.
6. Miravitles M., Soler-Catuluna J.J., Calle M. et al. Spanish COPD Guidelines: pharmacological treatment of stable COPD // Arch. Broncopneumol. — 2012. — Vol. 48. — P. 247-257.
7. Celli B.R., Decramer M., Wedzicha J.A. et al. An official American Thoracic Society/European Respiratory Society Statement: Research Questions in COPD // Am. J. Respir. Crit. Care Med. — 2015. — Vol. 191. — P. e4-27.
8. Han M.K., Augusti A., Calverley P.M. et al. Chronic obstructive pulmonary disease phenotypes: the future of COPD // Am. J. Respir. Crit. Care Med. — 2010. — Vol. 182. — P. 598-604.
9. Wardlaw A.J., Silverman M., Siva R. et al. Multi-dispersional phenotyping: towards a new taxonomy for air disease // Clin. Exp. Allergy. — 2005. — Vol. 35. — P. 1254-1262.
10. Weatherall M., Travers J., Shirtcliffte P.M. et al. Distinct clinical phenotypes of airways disease defined by cluster analysis // Eur. Respir. J. — 2009. — Vol. 34. — P. 812-818.
11. Burgel P.R., Paillasseur J.L., Caillaud D. et al. On behalf of the Initiatives BPCO Scientific Committee: Clinical COPD phenotypes: a novel approach using principal component and cluster analyses // Eur. Respir. J. — 2010. — Vol. 36. — P. 531-539.
12. Carolan B.J., Sutherland E.R. Clinical phenotypes of COPD and asthma: recent advances // J. Allergy Clin. Immunol. — 2013. — Vol. 131. — P. 627-634.
13. Fletcher C., Peto R. The natural history of chronic airflow obstruction // BMJ. — 1977. — Vol. 1. — P. 1645-1648.
14. Nishimura M., Makita H., Nagai K. et al. Annual change in pulmonary function and clinical phenotype in COPD // Am. J. Respir. Crit. Care Med. — 2012. — Vol. 185. — P. 44-52.
15. Vestbo J., Edwards L.D., Scanlon P.D. et al. Changes in forced expiratory volume in 1 second over time in COPD // N. Engl. J. Med. — 2011. — Vol. 365. — P. 1184-1192.
2. Vestbo J., Hurd S.S., Augusti A.G. et al. Global strategy for the diagnosis, management and prevention of COPD — GOLD executive summary // Am. J. Respir. Crit. Care Med. — 2013. — Vol. 187. — P. 347-365.
3. Bednarek M., Sliwinsky P. Fenotypy przewlekłej obturacyjnej choroby płuc // Terapia. — 2015. — № 9. — S. 6-11.
4. Pierzchala W. Fenotyp POChP: różnice patogenetyczne i terapeutyczne // Terapia. — 2016. — № 3. — S. 32-35.
5. Miravitles M., Calle M., Soler-Cataluna J.J. Clinical phenotypes of COPD: identification, definition and implications for guidelines // Arch. Broncopneumol. — 2012. — Vol. 48. — P. 86-98.
6. Miravitles M., Soler-Catuluna J.J., Calle M. et al. Spanish COPD Guidelines: pharmacological treatment of stable COPD // Arch. Broncopneumol. — 2012. — Vol. 48. — P. 247-257.
7. Celli B.R., Decramer M., Wedzicha J.A. et al. An official American Thoracic Society/European Respiratory Society Statement: Research Questions in COPD // Am. J. Respir. Crit. Care Med. — 2015. — Vol. 191. — P. e4-27.
8. Han M.K., Augusti A., Calverley P.M. et al. Chronic obstructive pulmonary disease phenotypes: the future of COPD // Am. J. Respir. Crit. Care Med. — 2010. — Vol. 182. — P. 598-604.
9. Wardlaw A.J., Silverman M., Siva R. et al. Multi-dispersional phenotyping: towards a new taxonomy for air disease // Clin. Exp. Allergy. — 2005. — Vol. 35. — P. 1254-1262.
10. Weatherall M., Travers J., Shirtcliffte P.M. et al. Distinct clinical phenotypes of airways disease defined by cluster analysis // Eur. Respir. J. — 2009. — Vol. 34. — P. 812-818.
11. Burgel P.R., Paillasseur J.L., Caillaud D. et al. On behalf of the Initiatives BPCO Scientific Committee: Clinical COPD phenotypes: a novel approach using principal component and cluster analyses // Eur. Respir. J. — 2010. — Vol. 36. — P. 531-539.
12. Carolan B.J., Sutherland E.R. Clinical phenotypes of COPD and asthma: recent advances // J. Allergy Clin. Immunol. — 2013. — Vol. 131. — P. 627-634.
13. Fletcher C., Peto R. The natural history of chronic airflow obstruction // BMJ. — 1977. — Vol. 1. — P. 1645-1648.
14. Nishimura M., Makita H., Nagai K. et al. Annual change in pulmonary function and clinical phenotype in COPD // Am. J. Respir. Crit. Care Med. — 2012. — Vol. 185. — P. 44-52.
15. Vestbo J., Edwards L.D., Scanlon P.D. et al. Changes in forced expiratory volume in 1 second over time in COPD // N. Engl. J. Med. — 2011. — Vol. 365. — P. 1184-1192.
Downloads
Download data is not yet available.